Onyx胶栓塞在脑动静脉畸形患者临床安全性及预后探究(1)
[摘要]目的 观察并探讨Onyx胶栓塞治疗对脑动静脉畸形(CAVM)的有效性和安全性。 方法 选择自2010年6月～2014年1月在本院住院治疗的CAVM患者96例，按照随机分组法将96例患者分为两组，观察组和对照组各48例，观察组给予Onyx胶栓塞治疗，而对照组给予NBCA胶栓塞治疗。治疗后统计两组患者的栓塞率≥80%比率、复发率、平均体积缩小、术后恢复时间和住院时间及并发症发生情况。 结果 观察组栓塞率≥80%比率、复发率分别为87.5%(42/48)和0，对照组为66.7%(32/48)和12.5%(6/48)，两组相比，差异有统计学意义(P<0.05)；观察组平均体积缩小、术后恢复时间和住院时间分别为(12.5±2.9)cm3、(25.4±4.9)h和(15.8±1.9)d，对照组为(9.6±2.4)cm3、(25.9±4.6)h和(16.2±1.8)d，两组平均体积缩小相比，差异具有统计学意义(P<0.05)；观察组并发症率为4.2%(2/48)，对照组为10.4%(5/48)，两组相比，差异无统计学意义(P>0.05)。 结论 Onyx胶栓塞治疗能明显改善CAVM患者的临床症状，疗效显著，是安全有效的疗法。
, 百拇医药
[关键词] Onyx胶；栓塞治疗；脑动静脉畸形
[中图分类号] R651 [文献标识码] B [文章编号] 2095-0616(2015)16-116-04
Clinical application and safety inquiry of Onyx glue embolization in patients with cerebral arteriovenous malformation
TANG Jianjian1.2 ZHANG Ziyin2 ZHOU Jian2 MA Chunyang2 WANG Zizhen2 HUANG Qiuhu2
1. Department of Neurosurgery， the First People's Hospital of Jintang， Jintang 610400， China； 2. Department of Neurosurgery， the Affiliated Hospital of Hainan Medical College， Haikou 570102， China
, 百拇医药
[Abstract] Objective To observe and explore the clinical value and safety of Onyx glue embolization in patients with cerebral arteriovenous malformation(CAVM). Methods 96 patients with CAVM in this hospital from June 2010 to January 2014 were selected， all the patients were randomized divided into two groups， 48 cases in the observation group and 48 cases in the control group， the observation group were treated with Onyx glue embolization， while the control group were treated with NBCA glue embolization. Occlusion rate ≥80%， recurrence rate， the average reduced volume， postoperative recovery time and hospital stay， as well as complications were observed in the two groups after treatment. Results The ratio of occlusion rate≥80% and recurrence in observation group was 87.5%(42/48) and 0， while was 66.7%(32/48) and 12.5%(6/48) in the control group， the difference was statistically significance(P<0.05)； the average reduced volume， postoperative recovery time and hospitalization time were (12.5±2.9)cm3，(25.4±4.9) h and (15.8±1.9)d in observation group， while was(9.6±2.4)cm3， (25.9±4.6)h and (16.2±1.8)d in the control group， the difference the average reduced volume between the two groups was statistically significant (P<0.05)； complication rate was 4.2%(2/48) in the observation group， and was 10.4%(5/48) in the control group， the difference was not statistically significant(P>0.05). Conclusion Onyx glue embolization can significantly improve the clinical symptoms of CAVM patients， with significant effect， thus is safe and effective therapy., 百拇医药(唐建建等)
, 百拇医药
[关键词] Onyx胶；栓塞治疗；脑动静脉畸形
[中图分类号] R651 [文献标识码] B [文章编号] 2095-0616(2015)16-116-04
Clinical application and safety inquiry of Onyx glue embolization in patients with cerebral arteriovenous malformation
TANG Jianjian1.2 ZHANG Ziyin2 ZHOU Jian2 MA Chunyang2 WANG Zizhen2 HUANG Qiuhu2
1. Department of Neurosurgery， the First People's Hospital of Jintang， Jintang 610400， China； 2. Department of Neurosurgery， the Affiliated Hospital of Hainan Medical College， Haikou 570102， China
, 百拇医药
[Abstract] Objective To observe and explore the clinical value and safety of Onyx glue embolization in patients with cerebral arteriovenous malformation(CAVM). Methods 96 patients with CAVM in this hospital from June 2010 to January 2014 were selected， all the patients were randomized divided into two groups， 48 cases in the observation group and 48 cases in the control group， the observation group were treated with Onyx glue embolization， while the control group were treated with NBCA glue embolization. Occlusion rate ≥80%， recurrence rate， the average reduced volume， postoperative recovery time and hospital stay， as well as complications were observed in the two groups after treatment. Results The ratio of occlusion rate≥80% and recurrence in observation group was 87.5%(42/48) and 0， while was 66.7%(32/48) and 12.5%(6/48) in the control group， the difference was statistically significance(P<0.05)； the average reduced volume， postoperative recovery time and hospitalization time were (12.5±2.9)cm3，(25.4±4.9) h and (15.8±1.9)d in observation group， while was(9.6±2.4)cm3， (25.9±4.6)h and (16.2±1.8)d in the control group， the difference the average reduced volume between the two groups was statistically significant (P<0.05)； complication rate was 4.2%(2/48) in the observation group， and was 10.4%(5/48) in the control group， the difference was not statistically significant(P>0.05). Conclusion Onyx glue embolization can significantly improve the clinical symptoms of CAVM patients， with significant effect， thus is safe and effective therapy., 百拇医药(唐建建等)