【摘要】 目的：探究颅骨缺损修复术后继发性癫痫的危险因素。方法：回顾性分析2014年10月-2017年12月于笔者所在医院神经外科因创伤行颅骨缺损修复术患者279例的临床资料。采用二元Logistic回归分析对颅骨缺损修复术后继发性癫痫的危险因素进行探讨。结果：279例患者中，颅骨缺损修复术后继发性癫痫39例(13.98%)。颅骨缺损区域面积、术前皮瓣凹陷深度均是颅骨缺损修补术后癫痫发作的独立危险因素[OR=2.079，95%CI(1.138，6.612);OR=1.011，95%CI(1.003，1.019)]，差异均有统计学意义(P<0.05)。结论：对于颅骨缺损区域面积大，术前皮瓣凹陷深度深的患者，术后应密切观察并预防癫痫发作。

    【关键词】 颅骨缺损修复术 继发性癫痫 危险因素

    doi：10.14033/j.cnki.cfmr.2019.29.004 文献标识码 A 文章编号 1674-6805(2019)29-000-03

    [Abstract] Objective： To analyze the risk factors of the secondary epilepsy after cranial defect repair. Method： The clinical data of 279 patients underwent cranial defect repair due to trauma in the neurosurgery department of the hospital from October 2014 to December 2017 were retrospectively analyzed. Binary Logistic regression analysis was used to explore the risk factors of the secondary epilepsy after cranial defect repair. Result： Among the 279 patients ......