体外反搏治疗高龄老年稳定性冠心病心绞痛及对6分钟步行距离的影响(1)
【摘要】 目的：观察体外反搏治疗高龄老年稳定性冠心病心绞痛及对6分钟步行距离(6MWT)的影响。方法：本试验共有96例高龄老年稳定性冠心病患者纳入研究，根据患者是否予体外反搏治疗，随机分为常规治疗组(n=48)和反搏治疗组(n=48)，常规治疗组按冠心病二级预防药物治疗，反搏治疗组在常规药物治疗基础上配合体外反搏治疗，治疗2个疗程后(共12周)，比较两组心绞痛治疗有效率，采用动态心电图分析比较两组心肌缺血时间，采用6分钟步行距离(6MWT)比较两组运动耐量情况。结果：体外反搏组心绞痛治疗总有效率明显高于常规治疗组，平均心肌缺血时间明显缩短，6MWT明显延长，差异均有统计学意义(P<0.05)。结论：体外反搏联合常规药物治疗能进一步减轻高龄老年稳定性冠心病患者心绞痛症状，改善心肌缺血，提高活动耐量，值得临床推广应用。
【关键词】 体外反搏； 稳定性冠心病； 老年； 6分钟步行距离
doi：10.14033/j.cnki.cfmr.2017.22.001 文献标识码 A 文章编号 1674-6805(2017)22-0001-02
Therapeutic Effect of External Counterpulsation on Elderly Patients with Stable Coronary Heart Disease and Their 6-minutes Walking Test/WANG Shi-hong.//Chinese and Foreign Medical Research，2017，15(22)：1-2
【Abstract】 Objective：To observe therapeutic effect of external counterpulsation(ECP) on elderly patients with stable coronary heart disease(SCHD) and their 6-minutes walking test(6MWT).Method：A total of 96 very elderly patients with SCHD were enrolled in the present study.All of the patients were classified into control group(n=48) and observation group(n=48) randomly，based on the presence of ECP or not.Control group was treated with secondary prevention medicine for CHD，and observation group accepted ECP treatment except the routine treatments.The differences of the total effective rate of angina pectoris，myocardial ischemia time detected by 24-hour dynamic electrocardiogram and the exercise capacity evaluated by 6MWT were observed between the two groups after following up for 12 weeks(2 courses).Result：The total effective rate of angina pectoris was significantly higher than that of control group，the difference was statistically significant(P<0.05).Compared with control group，observation group had a significantly shorten of myocardial ischemia time and had a significantly prolonged of 6MWT，the differences were statistically significant(P<0.05).Conclusion：Treatment of secondary prevention medicine with ECP can further relieve the symptom of angina pectoris，improve myocardial ischemi and increase the exercise capacity.It deserves to be extended.
【Key words】 Counterpulsation； Stable coronary heart disease； Elderly； 6-minutes walking test
First-author’s address：Fujian Provincial Geriatric Hospital，Fuzhou 350001，China
冠心病是人类健康的主要杀手，近年来，其发病率逐年攀升，严重威胁中老年人的身心健康。心绞痛是稳定性冠心病最常见的临床表现，药物治疗和血运重建手术是当今治疗冠心病心绞痛的两大主要手段[1]。然而，针对高龄稳定性冠心病患者，上述治疗手段在临床上常常不能获得理想的效果。反复心绞痛发作给患者带来极大的痛苦及心理负担，严重者甚至导致心肌梗死的发生。因此，对于高龄冠心病的治疗，寻找其他安全、有效治疗手段已成为心血管医生共同努力的方向。体外反搏(external counterpulsation，ECP)是一种新的无创性机械循环辅助治疗冠心病的方法，因其良好的安全性及有效性被广泛应用于冠心病心絞痛的治疗[2-3]。然而，体外反搏治疗高龄老年稳定性冠心病的研究鲜有报道。本研究以高龄老年稳定性冠心病患者为研究对象，观察体外反搏治疗稳定型心绞痛及对6 min步行距离的影响，现报道如下。, 百拇医药(王世红)
【关键词】 体外反搏； 稳定性冠心病； 老年； 6分钟步行距离
doi：10.14033/j.cnki.cfmr.2017.22.001 文献标识码 A 文章编号 1674-6805(2017)22-0001-02
Therapeutic Effect of External Counterpulsation on Elderly Patients with Stable Coronary Heart Disease and Their 6-minutes Walking Test/WANG Shi-hong.//Chinese and Foreign Medical Research，2017，15(22)：1-2
【Abstract】 Objective：To observe therapeutic effect of external counterpulsation(ECP) on elderly patients with stable coronary heart disease(SCHD) and their 6-minutes walking test(6MWT).Method：A total of 96 very elderly patients with SCHD were enrolled in the present study.All of the patients were classified into control group(n=48) and observation group(n=48) randomly，based on the presence of ECP or not.Control group was treated with secondary prevention medicine for CHD，and observation group accepted ECP treatment except the routine treatments.The differences of the total effective rate of angina pectoris，myocardial ischemia time detected by 24-hour dynamic electrocardiogram and the exercise capacity evaluated by 6MWT were observed between the two groups after following up for 12 weeks(2 courses).Result：The total effective rate of angina pectoris was significantly higher than that of control group，the difference was statistically significant(P<0.05).Compared with control group，observation group had a significantly shorten of myocardial ischemia time and had a significantly prolonged of 6MWT，the differences were statistically significant(P<0.05).Conclusion：Treatment of secondary prevention medicine with ECP can further relieve the symptom of angina pectoris，improve myocardial ischemi and increase the exercise capacity.It deserves to be extended.
【Key words】 Counterpulsation； Stable coronary heart disease； Elderly； 6-minutes walking test
First-author’s address：Fujian Provincial Geriatric Hospital，Fuzhou 350001，China
冠心病是人类健康的主要杀手，近年来，其发病率逐年攀升，严重威胁中老年人的身心健康。心绞痛是稳定性冠心病最常见的临床表现，药物治疗和血运重建手术是当今治疗冠心病心绞痛的两大主要手段[1]。然而，针对高龄稳定性冠心病患者，上述治疗手段在临床上常常不能获得理想的效果。反复心绞痛发作给患者带来极大的痛苦及心理负担，严重者甚至导致心肌梗死的发生。因此，对于高龄冠心病的治疗，寻找其他安全、有效治疗手段已成为心血管医生共同努力的方向。体外反搏(external counterpulsation，ECP)是一种新的无创性机械循环辅助治疗冠心病的方法，因其良好的安全性及有效性被广泛应用于冠心病心絞痛的治疗[2-3]。然而，体外反搏治疗高龄老年稳定性冠心病的研究鲜有报道。本研究以高龄老年稳定性冠心病患者为研究对象，观察体外反搏治疗稳定型心绞痛及对6 min步行距离的影响，现报道如下。, 百拇医药(王世红)