极低出生体重儿83例临床分析(1)
【摘要】 目的：探讨极低出生体重儿(VLBWI)的发生原因、并发症及预后。方法：将83例VLBWI按照孕周不同分为≤32周组(n=32)与>32周组(n=51)；按出生时体重不同分为≤1250 g组(n=20)与>1250 g组(n=63)，分析VLBWI的发生原因、并发症及预后。结果：≤32周组VLBWI感染、NRDS发生率均明显高于>32周组，预后也明显较差(P<0.05)。≤1250 g组呼吸暂停、感染、NRDS、低体温发生率均明显高于>1250 g组，预后也明显较差(P<0.05)。结论：VLBWI的发生原因较多，VLBWI胎龄越小、体重越轻，发生并发症的概率越高、预后越差。需加强各种并发症的防治，以提高VLBWI生存率及生存质量。
【关键词】 极低出生体重儿； 并发症； 预后； 临床分析
中图分类号 R722.6 文献标识码 B 文章编号 1674-6805(2016)6-0106-02
Clinical Analysis of 83 Cases of Very Low Birth Weight Infants/CHEN Mei-fang.//Chinese and Foreign Medical Research，2016，14(6)：106-107
【Abstract】 Objective：To explore the causes，complications and prognosis of very low birth weight infant(VLBWI).Method：According to the different gestational weeks，83 cases of VLBWI were divided into the ≤32 weeks group(n=32) and the >32 weeks group(n=51)，according to the weight postnatal，they were divided into the ≤1250 g group(n=20) and the >1250 g group(n=63)，the causes，complications and prognosis of VLBWI were analyzed.Result：The incidence rate of infect and neonatal respiratory distress syndrome(NRDS) in the ≤32 weeks group were significantly higher than those in the >32 weeks group(P<0.05)，the prognosis was significantly poor than that in the >32 weeks group(P<0.05).The incidence rate of apnea，infect， NRDS and hypothermia in the ≤1250 g group were significantly higher than those in the >1250 g group(P<0.05)，the prognosis was significantly poor than that in the>1250 g group(P<0.05).Conclusion：The causes of VLBWI was multiple.The incidence of complication and prognosis were much higher and poor in smaller gestational age infants and lighter weight in VLBWI.It need to strengthen the prevention and treatment of various complications，and to improve the survival and quality of life in VLBWI.
【Key words】 Very low birth weight infant； Comlication； Prognosis； Clinical analysis
First-author’s address：The People’s Hospital of Wuxuan，Wuxuan 545900，China
doi：10.14033/j.cnki.cfmr.2016.6.058
近年来，随着围产医学及新生儿监护诊疗技术的发展，极低出生体重儿(very low birth weight infant，VLBWI)存活率也越来越高[1]。但由于VLBWI胎龄小、各器官功能发育尚未成熟、免疫功能低下，常伴随着各种并发症的出现，导致VLBWI预后不良[2]。因此，深入了解VLBWI，积极防治并发症、提高其存活率和生存质量是新生儿医学重要课题。本文回顾性分析笔者所在医院收治的83例VLBWI临床资料，探讨其发生原因、并发症和防治措施及转归情况，为VLBWI的临床诊疗提供参考，现报告如下。
1 资料与方法
1.1 一般资料
选取2011年1月-2014年12月笔者所在医院新生儿重症监护室(NICU)收治的83例VLBWI，其中男50例，女33例。胎龄27～35周，平均(31.52±2.17)周；<30周12例(14.46%)，30～32周20例(24.10%)，>32周51例(61.45%)；经阴道产56例(67.47%)，剖宫产27例(32.53%)；出生时体重850～1500 g，平均(1246.17±105.82)g；<1000 g者5例(6.02%)，1000～1250 g者15例(18.07%)，>1250 g者63例(75.90%)。, http://www.100md.com(陈梅芳)
【关键词】 极低出生体重儿； 并发症； 预后； 临床分析
中图分类号 R722.6 文献标识码 B 文章编号 1674-6805(2016)6-0106-02
Clinical Analysis of 83 Cases of Very Low Birth Weight Infants/CHEN Mei-fang.//Chinese and Foreign Medical Research，2016，14(6)：106-107
【Abstract】 Objective：To explore the causes，complications and prognosis of very low birth weight infant(VLBWI).Method：According to the different gestational weeks，83 cases of VLBWI were divided into the ≤32 weeks group(n=32) and the >32 weeks group(n=51)，according to the weight postnatal，they were divided into the ≤1250 g group(n=20) and the >1250 g group(n=63)，the causes，complications and prognosis of VLBWI were analyzed.Result：The incidence rate of infect and neonatal respiratory distress syndrome(NRDS) in the ≤32 weeks group were significantly higher than those in the >32 weeks group(P<0.05)，the prognosis was significantly poor than that in the >32 weeks group(P<0.05).The incidence rate of apnea，infect， NRDS and hypothermia in the ≤1250 g group were significantly higher than those in the >1250 g group(P<0.05)，the prognosis was significantly poor than that in the>1250 g group(P<0.05).Conclusion：The causes of VLBWI was multiple.The incidence of complication and prognosis were much higher and poor in smaller gestational age infants and lighter weight in VLBWI.It need to strengthen the prevention and treatment of various complications，and to improve the survival and quality of life in VLBWI.
【Key words】 Very low birth weight infant； Comlication； Prognosis； Clinical analysis
First-author’s address：The People’s Hospital of Wuxuan，Wuxuan 545900，China
doi：10.14033/j.cnki.cfmr.2016.6.058
近年来，随着围产医学及新生儿监护诊疗技术的发展，极低出生体重儿(very low birth weight infant，VLBWI)存活率也越来越高[1]。但由于VLBWI胎龄小、各器官功能发育尚未成熟、免疫功能低下，常伴随着各种并发症的出现，导致VLBWI预后不良[2]。因此，深入了解VLBWI，积极防治并发症、提高其存活率和生存质量是新生儿医学重要课题。本文回顾性分析笔者所在医院收治的83例VLBWI临床资料，探讨其发生原因、并发症和防治措施及转归情况，为VLBWI的临床诊疗提供参考，现报告如下。
1 资料与方法
1.1 一般资料
选取2011年1月-2014年12月笔者所在医院新生儿重症监护室(NICU)收治的83例VLBWI，其中男50例，女33例。胎龄27～35周，平均(31.52±2.17)周；<30周12例(14.46%)，30～32周20例(24.10%)，>32周51例(61.45%)；经阴道产56例(67.47%)，剖宫产27例(32.53%)；出生时体重850～1500 g，平均(1246.17±105.82)g；<1000 g者5例(6.02%)，1000～1250 g者15例(18.07%)，>1250 g者63例(75.90%)。, http://www.100md.com(陈梅芳)