维甲酸治疗肺气肿的研究进展(1)
【摘要】 维甲酸通过拮抗蛋白酶来治疗肺气肿是目前临床上最有希望治疗药物。近年来的研究表明，各种因素致气道、肺组织的损害导致慢性阻塞性肺气肿形成，使得肺功能下降或障碍是不可逆损害，但应用维甲酸治疗可以改变肺气肿恢复的可逆性。本文主要介绍维甲酸治疗作用机制及其一些最新的研究进展，并重点探讨了与其抑制肺气肿形成的相互关系。【关键词】慢性阻塞性肺气肿;全反式维甲酸;炎性细胞;炎性介质;细胞因子
【Abstract】 That retinoic acid is treated emphysema by antiprotease, which is most promising clinical treatment of emphysemas drugs. Recent research shows that the various factors that cause the airway, lung tissue damage cause chronic obstructive pulmonary emphysema formation, which causes lung function decline or obstacle is irreversible damage, but the application of retinoid acid treatment can change emphysema reversibility of treatment. This paper mainly introduces retinoic acid treatment mechanism and some latest research progress, and probes into its suppression of relationship formed emphysema.
【Key words】 COPD; RA; Inflammatory cells; Inflammatory mediators; cytokines
目前临床上治疗COPD的方法有很多 ......
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