耳穴在老年腰椎术后患者的镇痛疗效及神经相关肽和心脏功能的研究(1)
摘要 目的：探討耳穴在老年腰椎术后患者的镇痛的疗效观察，同时观察机体神经相关肽和心脏功能的变化。方法：选取2014年1月至2016年1月无锡市中医医院全麻下行腰椎管减压、椎弓根钉内固定植骨融合术患者60例，随机分为对照组和观察组，每组30例。其中观察组患者术前1 d利用王不留行籽贴压耳穴，按揉3～5次/d，以耳廓发胀、发红为度，并保留至术后72 h。记录2组患者疼痛评分，并予麻醉前、术后24 h、术后72 h比较2组患者神经相关肽水平以及心脏功能。结果：1)术后24 h 2组患者VAS评分均较麻醉前有所提升，但此时2组患者的VAS评分之间差异无统计学意义(P>0.05)，至术后72 h 2组VAS评分逐渐下降，其中观察组下降的趋势更为明显，VAS评分明显低于对照组，差异有统计学意义(P<0.05)。2)麻醉24 h时2组NSE、S100、Aβ、cTnI含量均较麻醉前升高，差异有统计学意义(P<0.05)，至麻醉后72 h 2组NSE、S100、Aβ含量才逐渐减低，此时观察组降低得更为明显，与对照组比较差异有统计学意义(P<0.05)。结论：耳穴可有效缓解腰椎术后疼痛，并且可发挥保护神经功能及心脏的作用。
, 百拇医药
关键词 腰椎术后；耳穴；神经相关肽；心脏功能
Abstract Objective：To investigate the analgesia effect of auricular points in the elderly patients with postoperative lumbar， and to observe the changes of neuropeptide and cardiac function in the body. Methods：A total of 60 cases of patients who were received lumbar spinal canal decompression and vertebral pedicle screw fixation with bone grafting fusion under general anesthesia in our hospital from January 2014 to January 2016 were selected and randomly divided into the control group and the observation group， with 30 cases in each group. The patients of the observation group used auricular-seed-pressing therapy of cowherb seed the day before operation， and knead for 3 to 5 times a day until auricle swell and red， and keep till 72 h after operation. The VAS scores of patients of the two groups before anesthesia and 24 h， 72 h after operative were recorded， and the differences of the two groups with neuropeptide levels and cardiac function were compared. Results：1) VAS scores of the two groups improved postoperative 24 h when compared with before anesthesia， but VAS scores between the two groups were without statistically significant differences (P>0.05). VAS scores decreased significantly in both the two groups until postoperative 72 h， and the downward trend of observation group was more significant. VAS scores were significantly lower than the control group， and the differences were statistically significant (P<0.05). 2) The levels of NSE， S100， Aβ， cTnI at postoperative 24 h were higher than that before anesthesia in both groups， and the differences were statistically significant (P<0.05). NSE， S100 and Aβof the two groups postoperative 72 h reduced gradually， and the observation group reduced more significantly compared with the control group with statistically significant differences (P<0.05). Conclusion：Auricular points treatment can effectively relieve postoperative pain of lumbar， and play a role of protection of neurological function and heart., 百拇医药(章沁丹 尹卫娟 杨慧慧 蔡靓羽)
, 百拇医药
关键词 腰椎术后；耳穴；神经相关肽；心脏功能
Abstract Objective：To investigate the analgesia effect of auricular points in the elderly patients with postoperative lumbar， and to observe the changes of neuropeptide and cardiac function in the body. Methods：A total of 60 cases of patients who were received lumbar spinal canal decompression and vertebral pedicle screw fixation with bone grafting fusion under general anesthesia in our hospital from January 2014 to January 2016 were selected and randomly divided into the control group and the observation group， with 30 cases in each group. The patients of the observation group used auricular-seed-pressing therapy of cowherb seed the day before operation， and knead for 3 to 5 times a day until auricle swell and red， and keep till 72 h after operation. The VAS scores of patients of the two groups before anesthesia and 24 h， 72 h after operative were recorded， and the differences of the two groups with neuropeptide levels and cardiac function were compared. Results：1) VAS scores of the two groups improved postoperative 24 h when compared with before anesthesia， but VAS scores between the two groups were without statistically significant differences (P>0.05). VAS scores decreased significantly in both the two groups until postoperative 72 h， and the downward trend of observation group was more significant. VAS scores were significantly lower than the control group， and the differences were statistically significant (P<0.05). 2) The levels of NSE， S100， Aβ， cTnI at postoperative 24 h were higher than that before anesthesia in both groups， and the differences were statistically significant (P<0.05). NSE， S100 and Aβof the two groups postoperative 72 h reduced gradually， and the observation group reduced more significantly compared with the control group with statistically significant differences (P<0.05). Conclusion：Auricular points treatment can effectively relieve postoperative pain of lumbar， and play a role of protection of neurological function and heart., 百拇医药(章沁丹 尹卫娟 杨慧慧 蔡靓羽)