妇科千金片联合中药灌肠治疗慢性盆腔炎患者的疗效及对患者血液流变学、炎性因子水平的影响(1)
摘要 目的：探討妇科千金片联合中药灌肠治疗慢性盆腔炎的临床疗效及对患者血液流变学、炎性因子水平的影响。方法：选取2015年4月至2016年3月北京市西城区妇幼保健中心收治的慢性盆腔炎患者108例，并随机分为观察组和对照组，各54例。对照组采用常规治疗方法，观察组在对照组的基础上加用妇科千金片，2组均连续治疗14 d。评价2组患者临床疗效，检测并比较2组血流变学指标、炎性因子和生命质量的变化。结果：观察组总有效率为96.30%，显著高于对照组的85.19%(P<0.05)；治疗后2组全血高切、中切、低切黏度、血浆比黏度、红细胞聚集指数和纤维蛋白原均较治疗前显著下降(P<0.05或P<0.01)，且观察组显著低于对照组(P<0.05或P<0.01)；治疗后2组IL-2水平较治疗前显著上升，CRP、TNF-α水平及生命质量评分较治疗前显著下降(P<0.01)，且组间比较有统计学意义(P<0.05或P<0.01)。结论：妇科千金片联合中药灌肠治疗慢性盆腔炎效果确切，可有效降低患者体内炎性反应因子水平，改善血液高黏滞状态，提高患者生命质量。
, 百拇医药
关键词 慢性盆腔炎；妇科千金片；中药灌肠；血流变学；炎性因子；生命质量
Abstract Objective：To explore the curative effect of gynecological Qianjin pills combined with Chinese materia medica enema in the treatment of patients with chronic pelvic inflammatory disease and its influence on hemorheology and inflammatory factors. Methods：A total of 108 cases patients with chronic pelvic inflammatory disease were selected and randomly divided into the treatment group and the control group with 54 cases in each group. The control group was treated with conventional treatment， and the treatment group was treated with gynecological Qianjin pills on the basis of the control group. The 2 groups were treated continuously for 14 d. The clinical efficacy of the 2 groups was evaluated， and the changes of hemorheological indexes， inflammatory factors and quality of life in the 2 groups were detected and compared. Results：The total efficiency of the treatment group was 96.30%， which was significantly higher than 85.19% of the control group (P<0.05)； the 2 groups after treatment， whole blood high and low shear viscosity， plasma viscosity， erythrocyte aggregation index and fibrinogen were significantly lower than before treatment (P<0.05 or P<0.01)， and the treatment group was significantly lower than the control group (P<0.05 or P<0.01)； after treatment， levels of IL-2 in the 2 groups increased significantly， and levels of CRP， TNF-α and quality of life scores were significantly lower than before treatment (P<0.01)， and the difference between the 2 groups was significant (P<0.05 or P<0.01). Conclusion：The curative effect of gynecological Qianjin pills combined with chinese medicine enema in the treatment of patients with chronic pelvic inflammatory disease is accurate， which can effectively reduce the levels of inflammatory factors， improve the high viscosity state of blood， and improve the quality of life.
Key Words Chronic pelvic inflammatory disease； Gynecological Qianjin pills； Chinese materia medica enema； Hemorheology； Inflammatory factors； Life quality, 百拇医药(孙建荣 徐琦)
, 百拇医药
关键词 慢性盆腔炎；妇科千金片；中药灌肠；血流变学；炎性因子；生命质量
Abstract Objective：To explore the curative effect of gynecological Qianjin pills combined with Chinese materia medica enema in the treatment of patients with chronic pelvic inflammatory disease and its influence on hemorheology and inflammatory factors. Methods：A total of 108 cases patients with chronic pelvic inflammatory disease were selected and randomly divided into the treatment group and the control group with 54 cases in each group. The control group was treated with conventional treatment， and the treatment group was treated with gynecological Qianjin pills on the basis of the control group. The 2 groups were treated continuously for 14 d. The clinical efficacy of the 2 groups was evaluated， and the changes of hemorheological indexes， inflammatory factors and quality of life in the 2 groups were detected and compared. Results：The total efficiency of the treatment group was 96.30%， which was significantly higher than 85.19% of the control group (P<0.05)； the 2 groups after treatment， whole blood high and low shear viscosity， plasma viscosity， erythrocyte aggregation index and fibrinogen were significantly lower than before treatment (P<0.05 or P<0.01)， and the treatment group was significantly lower than the control group (P<0.05 or P<0.01)； after treatment， levels of IL-2 in the 2 groups increased significantly， and levels of CRP， TNF-α and quality of life scores were significantly lower than before treatment (P<0.01)， and the difference between the 2 groups was significant (P<0.05 or P<0.01). Conclusion：The curative effect of gynecological Qianjin pills combined with chinese medicine enema in the treatment of patients with chronic pelvic inflammatory disease is accurate， which can effectively reduce the levels of inflammatory factors， improve the high viscosity state of blood， and improve the quality of life.
Key Words Chronic pelvic inflammatory disease； Gynecological Qianjin pills； Chinese materia medica enema； Hemorheology； Inflammatory factors； Life quality, 百拇医药(孙建荣 徐琦)
参见：首页 > 医疗版 > 疾病专题 > 妇产科 > 女性生殖器官炎症 > 盆腔腹膜炎(盆腔炎)