摘要 目的：详述近些年国内外关于壳聚糖改性的制备方法，为更好的改善壳聚糖的水溶性提供更多、更有效的理论支撑。同时阐述壳聚糖在医药行业的广泛应用。方法：通过查阅国内外关于壳聚糖的文献，综述近年来国内外关于壳聚糖的研究进展。结果：壳聚糖改性后可以提高其水溶性，拓宽其应用领域。结论：初步概括了壳聚糖的修饰方法和实际应用。为充分挖掘和发挥壳聚糖的潜在价值、深入研究和开发应用提供参考。

    关键词 壳聚糖；水溶性；修饰

    Abstract Objective：To describe the preparation methods of modified chitosan in recent years specifically and provide much more and more effective theoretical support for improving the solubility of chitosan， and to illustrate the wide application of chitosan in the pharmaceutical industry. Methods：By referring to the domestic and foreign literatures on chitosan ......