含人参中成药用药规律分析(3)
SHEN Dan1， TANG Shi-huan1， LU Peng1，2， YANG Hong-jun1*
(1.Institute of Chinese Materia Medica， China Academy of Chinese Medical Sciences， Beijing 100700， China；
2. Institute of Automation， Chinese Academy of Sciences， Beijing 100190， China)
[Abstract] Use traditional Chinese medicine inheritance support system (TCMISS) to analyze the composition principles of Chinese patent drugs containing Renshen (Panax ginseng) in national standard for Chinese patent drugs (NSCPD) enacted by Ministry of Public Health of China. Via analyzing the regularity of prescriptions containing Ginseng which are recorded in NSCPD， to identify composition pattern and rule. Tweenty four drugs are used more than 50 times， in which，drugs that tonify qi and nourish flood have the highest frequency， and then medicines of liver and kidney tonifying， yin enriching and yang warming follow. Then 45 commonly used core combinations are analyzed via data mining methods such as association rules， improved mutual information method， etc. Meantime， three diseases， namely， palpitation， amnesia and chest discomfort are chosen from the 24 diseases that Ginseng most frequently used to make deeper analysis， which reflect the composition principle of Chinese patent drugs containing Ginseng. Therefore， TCMISS is an important tool in composition principle exploring of herbal formulae and meanwhile， the comparative analysis method contributes a lot to the exploration as well.
[Key words] Ginseng； national standard for Chinese patent drugs (NSCPD)； traditional Chinese medicine inheritance support system (TCMISS)； composition principle of prescription
doi：10.4268/cjcmm20131237, 百拇医药(申丹 唐仕欢 卢朋 杨洪军)
(1.Institute of Chinese Materia Medica， China Academy of Chinese Medical Sciences， Beijing 100700， China；
2. Institute of Automation， Chinese Academy of Sciences， Beijing 100190， China)
[Abstract] Use traditional Chinese medicine inheritance support system (TCMISS) to analyze the composition principles of Chinese patent drugs containing Renshen (Panax ginseng) in national standard for Chinese patent drugs (NSCPD) enacted by Ministry of Public Health of China. Via analyzing the regularity of prescriptions containing Ginseng which are recorded in NSCPD， to identify composition pattern and rule. Tweenty four drugs are used more than 50 times， in which，drugs that tonify qi and nourish flood have the highest frequency， and then medicines of liver and kidney tonifying， yin enriching and yang warming follow. Then 45 commonly used core combinations are analyzed via data mining methods such as association rules， improved mutual information method， etc. Meantime， three diseases， namely， palpitation， amnesia and chest discomfort are chosen from the 24 diseases that Ginseng most frequently used to make deeper analysis， which reflect the composition principle of Chinese patent drugs containing Ginseng. Therefore， TCMISS is an important tool in composition principle exploring of herbal formulae and meanwhile， the comparative analysis method contributes a lot to the exploration as well.
[Key words] Ginseng； national standard for Chinese patent drugs (NSCPD)； traditional Chinese medicine inheritance support system (TCMISS)； composition principle of prescription
doi：10.4268/cjcmm20131237, 百拇医药(申丹 唐仕欢 卢朋 杨洪军)