淫羊藿及其活性成分对心血管疾病的改善作用机制研究进展(6)
[57] 吴雨婷，李叶丽，付舒，等.淫羊藿次苷Ⅱ通过改善内质网应激和caspase-12 信号改善SHR大鼠左心室功能[J].中国药理学通报，2019，35(4)：571-575.
[58] SONG YH，CAI H，ZHAO ZM，et al. Icariin attenuated oxidative stress induced-cardiac apoptosis by mitochondria protection and ERK activation[J]. Biomed Pharmacother，2016.DOI：10.1016/j.biopha.2016.08.016.
[59] ZHOU H，YUAN Y，LIU Y，et al. Icariin attenuates angiotensin Ⅱ-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways[J]. Exp Ther Med，2014，7(5)：1116-1122.
[60] ZHANG Q，LI H，WANG S，et al. Icariin protects rat cardiac H9c2 cells from apoptosis by inhibiting endoplasmic reticulum stress[J]. Int J Mol Sci，2013，14(9)：17845- 17860.
[61] CHEN Y，SUN T，WU J，et al. Icariin intervenes in cardiac inflammaging through upregulation of SIRT6 enzyme activity and inhibition of the NF-kappa B pathway[J]. Biomed Res Int，2015.DOI：10.1155/2015/895976.
[62] ZHOU H，YUAN Y，LIU Y，et al. Icariin protects H9c2 cardiomyocytes from lipopolysaccharide?induced injury via inhibition of the reactive oxygen species?dependent c?Jun N?terminal kinases/nuclear factor-κB pathway[J]. Mol Med Rep，2015，11(6)：4327-4332.
(收稿日期：2019-12-07 修回日期：2020-03-08)
(編辑：唐晓莲), http://www.100md.com(方东菲 张建永)
[58] SONG YH，CAI H，ZHAO ZM，et al. Icariin attenuated oxidative stress induced-cardiac apoptosis by mitochondria protection and ERK activation[J]. Biomed Pharmacother，2016.DOI：10.1016/j.biopha.2016.08.016.
[59] ZHOU H，YUAN Y，LIU Y，et al. Icariin attenuates angiotensin Ⅱ-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways[J]. Exp Ther Med，2014，7(5)：1116-1122.
[60] ZHANG Q，LI H，WANG S，et al. Icariin protects rat cardiac H9c2 cells from apoptosis by inhibiting endoplasmic reticulum stress[J]. Int J Mol Sci，2013，14(9)：17845- 17860.
[61] CHEN Y，SUN T，WU J，et al. Icariin intervenes in cardiac inflammaging through upregulation of SIRT6 enzyme activity and inhibition of the NF-kappa B pathway[J]. Biomed Res Int，2015.DOI：10.1155/2015/895976.
[62] ZHOU H，YUAN Y，LIU Y，et al. Icariin protects H9c2 cardiomyocytes from lipopolysaccharide?induced injury via inhibition of the reactive oxygen species?dependent c?Jun N?terminal kinases/nuclear factor-κB pathway[J]. Mol Med Rep，2015，11(6)：4327-4332.
(收稿日期：2019-12-07 修回日期：2020-03-08)
(編辑：唐晓莲), http://www.100md.com(方东菲 张建永)